<optgroup id="eskm2"><optgroup id="eskm2"></optgroup></optgroup>
<nav id="eskm2"><code id="eskm2"></code></nav>
  • <xmp id="eskm2"><menu id="eskm2"></menu>
    <menu id="eskm2"><menu id="eskm2"></menu></menu>
    <nav id="eskm2"><strong id="eskm2"></strong></nav>
    <input id="eskm2"></input>
  • <menu id="eskm2"><strong id="eskm2"></strong></menu>
    <menu id="eskm2"></menu>
  • 生物科學與工程學院

    College of Biological Science and Engineering

    呂旭聰

    發布日期:2021-09-29 發布者:生工學院

    姓名:呂旭聰

    性別:







    職稱:研究員/博導(破格)

    學歷:博士

    電話:13960883103

    電子郵件:xucong1154@163.com

    研究方向:健康食品生物制造、食品與腸道微生物組學、釀造微生物代謝調控、食品營養與功能

    教育工作經歷:

    2022年1月-至今:福州大學 | 生物科學與工程學院 | 校聘研究員(旗山學者)、博士生導師

    2020年6月-2021年12月:福州大學 | 生物科學與工程學院 | 副研究員(旗山學者)、博士生導師


    2013年8月-2020年5月:福建農林大學 | 國家菌草工程技術研究中心 | 副研究員(金山學者)

    2013年3月-2013年7月:廈門大學 | 環境與生態學院 | 助理、工程師

    2007年9月-2013年2月:福州大學 | 化學化工學院 | 分析化學 | 博士(提前攻博)

    2003年9月-2007年7月:福州大學 | 生物科學與工程學院 | 生物工程 | 本科(保研)

     

    292DE

    教學簡介:

    主要承擔研究生《功能食品評價原理及方法》和本科生《食品微生物學》、《生物化學》、《食品化學》等教學。

    科研簡介:

    博士期間師從國際食品科技聯盟前主席饒平凡教授和福建省食品科學技術學會理事長倪莉教授,現任職于福州生物科學與工程學院、福州大學石油化工學院生物與醫藥專業博士生導師(破格晉升)。獲福建省自然科學“杰出青年”基金,入選福建省高校“杰出青年”科研人才計劃、福州大學“旗山學者”獎勵計劃、福建農林大學“金山學者”青年人才和校“杰出青年”人才計劃、泉州市高級人才。主持承擔國家自然科學基金面上項目和青年項目、中國博士后科學基金特別資助和一等資助項目、福建省自然科學“杰出青年”基金、福建省自然科學基金重點項目和面上項目,以第一/通訊作者在國內外期刊發表學術論文130篇,包括Carbohyd. Polym., Int. J. Biol. Macromol., J. Agric. Food Chem., Food Microbiol., Food Chem., Food Control, Food Res. Int., Food & Funct. 等國際期刊SCI文章70多篇(其中,期刊封面2篇,ESI高被引2篇),EI期刊文章16篇,H指數25,總影響因子超過300。研究工作受國內和國際同行的廣泛認可,發表的論文被引頻次1300多次,被J. Agric. Food Chem., Food Microbiol., Food Control, Int. J. Food Microbiol., Food & Funct.Int. J. Biol. Macromol. 等食品與生物工程領域國際權威學術期刊的文章廣泛引用,為福州大學“農業科學”進入ESI學科全球排名前1%發揮著積極的貢獻作用,以第一發明人申請國家發明專利9項,授權發明專利2項(已轉化1項),參與制定福建省地方標準和企業標準2項。

    近年來擔任國家自然科學基金項目通訊同行評審專家(食品科學)、國際微生物領域權威SCI期刊Frontiers in Microbiology [中科院二區]編委、中國食品科學技術學會釀造食品分會理事、福建省食品科學技術學會理事、J. Agric. Food Chem., Food Microbiol., Food Control, Carbohyd. Polym., Food Res. Int., Int. J. Biol. Macromol.Food & Funct. 等三十多個國際權威學術期刊評審專家,獲Elsevier旗下Food Control, Int. J. Food Microbiol., Int. J. Biol. Macromol.和英國皇家化學會旗下Food & Funct.等SCI期刊“杰出審稿人”稱號;近年來帶領的課題組在我國重要食藥用菌和益生菌功效作用領域做了深入的研究,其中靈芝酸A緩解高脂血癥的作用機制研究被英國皇家化學會(RSC)旗下《Food & Function》評選為期刊封面論文[Food & Funct., 2020, 11: 6818-6833.],這也是靈芝首次被刊登到英國皇家化學學會旗下的期刊封面上;紅曲酒來源的益生菌發酵海帶改善脂質代謝紊亂作用機制研究被《Food & Function》評選為期刊封面論文[Food & Funct., 2021, 12, 7096-7096.],這是我國紅曲酒相關微生物首次被刊登到國際權威期刊的封面上。藥用菌多糖(肽)介導腸道微生物組改善機體糖脂代謝的研究工作[Food & Funct., 2019, 10: 2560-2572.J. Func. Foods, 2019, 57: 48-58.]入選ESI學科高被引論文。

    作為第二完成人完成的《嶺南傳統發酵食品功能菌群解析及其發酵調控關鍵技術的研究與應用》項目經專家組評價為國際領先水平;紅曲酒釀造微生物組及其代謝調控研究榮獲中國博士后基金一等資助、特別資助;獲國際食品微生物與食品安全大會優秀論文獎、第十六屆國際食品科學技術大會優秀論文獎并被邀到巴西做學術報告、中國食品科學技術學會科技創新獎—技術進步獎二等獎、福建省科學技術進步獎二等獎、福建省自然科學優秀學術論文一等獎、福建省食品科學技術學會優秀學術論文一等獎。所指導的碩士研究生(含聯合培養)有6人榮獲“研究生國家獎學金”資助,有4人榮獲得校級“優秀碩士論文”,有1人被推薦為福建省“優秀碩士論文”,已有4人到國家“雙一流”大學(江南大學、華南理工大學、暨南大學)和香港中文大學繼續攻讀博士學位。

    研究領域健康食品生物制造、食品與腸道微生物組學、釀造微生物代謝調控、食品營養與功能組學。

    (1)傳統發酵食品菌群、風味、功能因子和危害物:探究典型傳統發酵食品(紅曲黃酒、永春老醋、釀造醬油...)發酵過程中的微生物菌群及其代謝功能,通過酶系、菌系和物系間的互作關系解析核心功能菌群,確定與特征香氣、功能因子、危害物等形成密切相關的功能微生物并解析其代謝調控機制,為傳統發酵食品的產業化發展奠定基礎。

    (2)傳統發酵食品釀造微生物代謝調控:傳統發酵食品中的原生菌群系統具有復雜、穩定性差和功能冗余等缺陷,導致不良副產物生成的同時也會增加發酵產品品質和風味的波動性,在釀造菌群多維宏組學分析研究的基礎上,通過釀造功能菌群的人工合成、組裝與調控,解決傳統發酵食品風味、安全與健康等制約產業發展的瓶頸問題。

    (3)食品功能因子遞送與腸道菌群互作研究:基于功能材料理性設計及納米生物技術,實現食品功能因子的增效遞送;通過腸菌宏基因組、蛋白質組及代謝組等多維組學技術,系統地研究閩臺特色食品(紅曲、食用菌、茶...)中功能因子改善機體健康和腸道穩態的分子機制,解決食品功能因子增效遞送與功效評價領域的共性關鍵技術問題。

    (4)食品功能因子的分子營養學與功能組學研究:立足<健康中國2030>國家戰略需求,關注閩臺特色食品功能因子健康效應與機制關鍵科學問題,運用營養基因組學、蛋白組學、代謝組學等前沿生命科學技術,系統研究閩臺地方特色食品及其功能因子對機體健康的調控機制,為我國慢性病預防和飲食干預管理提供科學依據。

    科研平臺:福州大學食品科技研究所(旗山校區科技園)、福州大學食品營養與健康研究中心(福大晉江校區)

    社會兼職:

    國家自然科學基金項目通訊評審專家<食品科學>

    國際SCI期刊Frontiers in Microbiology [中科院二區]編委、客座副主編

    中國食品科學技術學會釀造食品分會理事

    福建省食品科學技術學會理事

    福建省微生物學會微生物組與益生菌專業委員會委員

    福建省科技特派員<2020年>

    福建省科技特派員<2021年>

    福州市科技特派員<2020年>

    福州市科技特派員<2021年>

    J. Agric. Food Chem., Food Microbiol., Food Control, Carbohyd. Polym., Food Res. Int., Int. J. Biol. Macromol.Food & Funct.等三十多個國際SCI期刊評審專家

    科研項目:

    1. 國家自然科學基金青年項目基于靶向活菌的方法解析紅曲黃酒釀造體系中的功能菌群及其對香氣特征形成的調控機制,項目編號31601466,2017年-2019年,25萬,主持;

    2. 國家自然科學基金面上項目銨鹽補償對紅曲黃酒傳統釀造過程中高級醇和關鍵酯類生成的雙向調控機制研究,項目編號32072204,2021年-2024年,69.6萬,主持;

    3. 福建省自然科學“杰出青年”基金:紅曲黃酒釀造微生物組及其代 謝調控機制研究項目編號2019J06013,2019年-2021年,30萬,主持;

    4. 福建省高校“杰出青年”科研人才:靈芝多糖-鉻(III)超分子組裝及其改善高脂飲食小鼠糖脂代謝的分子機制研究,閩教科〔2017〕52號,2017年-2020年,8萬,主持;

    5. 中國博士后科學基金一等資助項目紅曲黃酒傳統釀造體系中微生物菌群的“原位”功能解析,項目編號2015M570549,2015年-2017年,10萬,主持;

    6. 中國博士后科學基金特別資助項目基于蛋白組學解析紅曲黃酒關鍵特征香氣組分的形成機理,項目編號2016T90591,2016年-2018年,18萬,主持;

    7. 福州大學旗山學者人才計劃科研項目:乳酸菌強化對紅曲酒傳統釀造過程生物胺生成的消減調控作用研究,項目編號GXRC21049,2021年-2024年,30萬,主持;

    8. 福建農林大學“金山學者”青年人才計劃:食品科學與工程(食品微生物組學)項目編號XJQ201607,2016年-2020年,9萬,主持;

    9. 福建省自然科學基金面上項目:灰樹花多糖介導腸道微生物調控脂質代謝的分子機制研究,項目編號2016J01095,2016年-2019年,5萬,主持;

    10. 福建省教育廳科技計劃A類項目:紅曲黃酒傳統釀造過程中代謝活性菌群結構與功能的研究,項目編號JA14107,2014年-2017年,2萬,主持;

    11. 福建農林大學“校杰出青年人才”計劃:靈芝多糖-鉻(III)納米超分子組裝及其改善高脂飲食大鼠糖脂代謝的分子機制,2017年-2019年,30萬,主持;

    12. 國家菌草工程技術研究中心開放課題:重金屬鎘離子特異性免疫檢測抗原的合成與表征,項目編號JCJJ14021,2014年-2015年,5萬,主持;

    13. 福建農大青年教師A類人才科研啟動基金:基于宏蛋白質組學技術研究紅曲黃酒傳統釀造用曲中的微生物菌群結構與功能,項目編號KXML2012A,2013年-2018年,5萬,主持;

    14. 食品質量與安全北京實驗室開放課題:紅曲黃酒傳統釀造體系中微生物菌群結構及特征香氣組分形成機理,項目編號FQS-201802,2018年-2019年,5萬,主持;

    15. 中加食品營養與健康聯合實驗室開放課題:基于腸道微生態調節的苦蕎麥乳酸菌發酵產品的降血脂作用機制研究,項目編號ZJ-2020-03,2020年-2021年,5萬,主持;

    16. 國家自然科學基金面上項目:基于DGGE技術的微生物生態學研究新方法的構建及其在紅曲黃酒釀造體系中的應用,項目編號31371820,2014-01至2017-12,80萬,已結題,主要完成人;

    17. 國家自然科學基金面上項目:釀造紅曲黃酒的主要微生物代謝生香特性與機制研究,項目編號31171733,2012-01至2015-12,62萬,已結題,主要完成人;

    18. 國家自然科學基金青年項目:基于蛋白質組學的灰樹花蛋白肽-硒螯合物對Caco-2細胞代謝的作用機制研究,項目編號31501432,2016/01至2018-12,20萬,已結題,第二完成人;

    19. 福建省科技廳重點項目:紅曲黃酒釀造用菌種庫的構建與應用,項目編號2011N0016,2011-04至2014-03,10萬元,已結題,主要完成人;

    20. 國家自然科學基金面上項目:應用微生物分子生態學技術研究紅曲黃酒釀造系統中的菌群結構,項目編號31071587,2011/01至2012-12,20萬,已結題,主要完成人;

    近三年發表論文情況(*通訊作者)

    1. Lv X.*,#, Chen M.#, Huang Z., Guo W., Ai L., Bai W., Yu X., Liu Y.*, Rao P., Ni L.. Potential mechanisms underlying the ameliorative effect of Lactobacillus paracasei FZU103 on the lipid metabolism in hyperlipidemic mice fed a high-fat diet. Food Res. Int., 2021, 139, 109956.

    2. Chen G.#, Huang Z.#, Wu L.#, Wu Q., Guo W., Liu B., Zhang W., Rao P., Zhang W., Rao P., Lv X.*, Ni L.*, Sun J.*, Sun B. Microbial diversity and flavor of Chinese rice wine (Huangjiu): an overview of current research and future prospects. Current Opinion in Food Science: Food Microbiology 2021, Vol 38. https://doi.org/10.1016/j.cofs.2021.02.017

    3. Zhang J., Zhang C., Wu W., Lv X., et al. Correlation of the bacterial communities with umami components, and chemical characteristics in Zhejiang xuecai and fermented brine. Food Res. Int., 2021, 140: 109986.

    4. Zhang C., Li J., Chen L., Shi X., Chen B., Lv X.*, Ni L.*. Effects of alkali, enzymes, and ultrasound on monosodium glutamate byproduct for a sustainable production of Bacillus subtilis. Food Chem., 2021. doi.org/10.1016/j.foodchem.2021.129967.

    5. Li T.#, Huang Z.#, Jia R., Lv X.*, Zhao C.*, Liu B.*. Spirulina platensis polysaccharides attenuate lipid and carbohydrate metabolism disorder in high-sucrose and high-fat diet-fed rats in association with intestinal microbiota. Food Res. Int., 2021. DOI: 10.1016/j.foodres.2021.110530.

    6. Zhou K., Wu L., Liu Z., Zhao X, Zhang C., Lv X.*, Zhang W, Rao P., Ni L.* Development of a novel restrictive medium for Monascus enrichment from Hongqu based on the synergistic stress of lactic acid and ethanol. Front. Microbiol., 2021. DOI: 10.3389/fmicb.2021.702951.

    7. Zhang Q.#, Fan X.#, Cao Y.#, Zheng T., Cheng W., Chen L., Lv X.*, Rao P., Ni L., Liang P.*. The beneficial effects of Lactobacillus brevis FZU0713-fermented Laminaria japonica on lipid metabolism and intestinal microbiota in hyperlipidemic rats fed a high-fat diet. Food & Function, 2021, 12, 7096-7096. [封面文章]

    8. Fan X.#, Zhang Q.#, Guo W.#, Wu Q., Hu J., Cheng W., Lv X.*, Rao P., Ni L., Chen Y.*, Chen L.*. The protective effects of Levilactobacillus brevis FZU0713 on lipid metabolism and intestinal microbiota in hyperlipidemic rats. Food Science and Human Wellness, 2021 (In publication).

    9. Wu L., Zhou K., Chen F., Chen G., Yu Y., Lv X.*, Ni L.*. Comparative Study on the Antioxidant Activity of Monascus Yellow Pigments from Two Different Types of Hongqu——Functional Qu and Coloring Qu. Front. Microbiol., 2021, doi: 10.3389/fmicb.2021.715295.

    10. Lin Y.#, Chen H.#, Cao Y.#, Zhang Y., Li W., Guo W., Lv X.*, Rao P., Ni L., Liu P.*. Auricularia auricula Melanin Protects against Alcoholic Liver Injury and Modulates Intestinal Microbiota Composition in Mice Exposed to Alcohol Intake. Foods, 2021, 10, 2436. https://doi.org/10.3390/foods10102436.

    11. Zhang W., Tong Q., You J., Lv X., Liu Z, Ni L.*. The Application of Bacillus subtilis for Adhesion Inhibition of Pseudomonas and Preservation of Fresh Fish. Foods, 2021, 10(12), 3093. https://doi.org/10.3390/foods10123093.

    12. Lv X.#, Wu Q.#, Cao Y., Lin Y., Zhang Y., Guo W.*, Rao P., Zhang Y., Chen Y., Ai L., Ni L.*. Ganoderic acid A from Ganoderma lucidum protects against alcoholic?liver?injury through ameliorating lipid metabolism and modulating intestinal microbial composition. Food & Function, 2022. https://doi.org/10.1039/D1FO03219D

    13. Zhao W., Qian M., Dong H.*, Liu X., Bai W.*, Liu G., Lv X.. Effects of Hong Qu on the flavor and quality of Hakka yellow rice wine (Huangjiu) produced in southern China. LWT - Food Science and Technology, 2022, 160, 113264. https://doi.org/10.1016/j.lwt.2022.113264

    14. Guo W.#, Cao Y.#, You S., Wu Q., Zhang F., Han J., Lv X.*, Rao P., Ai L., Ni L.*. Ganoderic acids-rich ethanol extract from Ganoderma lucidum protects against alcoholic?liver?injury and modulates intestinal microbiota in mice with excessive alcohol intake. Current Research in Food Science, 2022, 5: 515-530. https://doi.org/10.1016/j.crfs.2022.02.013

    15. Zhang F., Gao C., Bai L., Chen Y., Liang S., Lv X., Sun J.*, Wang S.*. Dual-color blending based visual LAMP for food allergen detection: a strategy with enlarged color variation range and contrast. Food Chemistry: X, 2021. https://doi.org/10.1016/j.fochx.2021.100201

    16. Bai L., Wang L., Huang S., Bai R., Lv X., Sun L., Zhang F.*, Xu X.*. Rapid, Visual, and Sequence-Specific Detection of Salmonella in Egg Liquid with vis-NEAA, a CRISPR/Cas12 Empowered New Strategy. J. Agric. Food Chem. 2022. https://doi.org/10.1021/acs.jafc.1c06715.

    17. Zhang Q.#, Guo W.#, Chen G., Wu Q., Han J., Lv X.*, Chen L., Rao P., Ai L., Ni L.*. Pediococcus acidilactici FZU106 alleviates high-fat diet-induced lipid metabolism disorder in association with the modulation of intestinal microbiota in hyperlipidemic rats. Current Research in Food Science, 2022 (In publication).

    18.Cao Y., Huang Z., You S., Guo W., Zhang F., Liu B., Lv X.*, Lin Z., Liu P.*. The Protective Effects of Ganoderic Acids from Ganoderma lucidum Fruiting Body on Alcoholic Liver Injury and Intestinal Microflora Disturbance in Mice with Excessive Alcohol Intake. Foods, 2022, 11, 949. https://doi.org/10.3390/foods11070949.

    19. Chen W.*, Lv X., Tran V.-T., Maruyama J.-i., Han K.-H., Yu J.-H.. Editorial: From Traditional to Modern: Progress of Molds and Yeasts in Fermented-Food Production. Front. Microbiol. -Food Microbiology, 2022. https://doi.org/10.3389/fmicb.2022.876872.

    20. Huang Z., Zhao L., Zhu F., Liu Y., Xiao J,, Chen Z., Lv X.*, Huang Y*., Liu B.*. Anti-Diabetic Effects of Ethanol Extract from Sanghuangporous vaninii in High-Fat/Sucrose Diet and Streptozotocin-Induced Diabetic Mice by Modulating Gut Microbiota. Foods, 2022, 11, 974. https://doi.org/10.3390/foods11070974

    21. Su W., Gao S., Zhan S., Wu Q., Chen G., Han J., Lv X.*, Rao P., Ni L.*. Evaluation of Volatile Profile and In Vitro Antioxidant Activity of Fermented Green Tea Infusion With Pleurotus sajor-caju (Oyster Mushroom). Frontiers in Nutrition, 2022. 9: 865991. https://doi.org/10.3389/fnut.2022.865991.

    22. Lv X., Yuan Y., Li W., Li L., Chen G., You W., Guo W.*, Rao P., Ai L., Ni L.*. Organic chromium derived from the chelation of Ganoderma lucidum polysaccharide-chromium (III) alleviates metabolic syndromes and intestinal microbiota dysbiosis induced by high-fat and high-fructose diet. Int. J. Biol. Macromol., 2022. (Under review).

    23. Wang M.#, Guo W.#, Yang Z., Tong S., Li W., You W., Lv X.*, Rao P., Ai L., Ni L.*. Intestinal microbiome and liver metabolomics insights into the preventive effects of chromium (III)-enriched yeast on hyperlipidemia and hyperglycemia induced by high-fat and high-fructose diet. Current Research in Food Science, 2022. (Under review).

    24. Chen G., Tong S., Li W., You W., Guo W., Wu Q., Lv X.*, Rao P., Ai L., Ni L.*. Comparative evaluation of the microbial communities and metabolic profiles in the traditional production of Hongqu rice wine fermented with Wuyi Qu and Gutian Qu. J. Agric. Food Chem., 2022. (In preparation)..

    25. Lv X.*, Wu Q., Xiao Y., Huang Z., Guo W., Hong J., Rao P., Ni L.*. Characterizing the dynamics of microbial community and flavor metabolites during the traditional fermentation of Chinese Hongqu aged vinegar. Food Microbiol., 2022. (In preparation)..

    26. Lv X.*, Li J., Huang Z., Wu Q., Guo W., Zhang Y., Rao P., Ai L., Ni L.*. Intestinal microbiome and liver metabolomics insights into the preventive effects of Lactobacillus rhamnosus GG on alcoholic liver injury in mice with excessive alcohol intake. Current Research in Food Science, 2022. (Under review).

    27. Lv X.*, Li J., Huang Z., Wu Q., Guo W., Zhang Y., Rao P., Ai L., Ni L.*. The protective effects of Leuconostoc citreum FZU3103 on alcoholic liver injury and intestinal microbial disorder in mice with excessive alcohol intake. Food Research International, 2022. (Under review).

    28. Lin Y.#, Cao Y., Guo W.#, Han J., Chen G., Lv X.*, Rao P., Ni L.*. Auricularia auricula polysaccharide protects against alcoholic?liver?injury and modulates intestinal microbiota in mice with excessive alcohol intake. Food & Function, 2022. (Under review).

    29. Cao Y.#, Guo W., Lin Y., Rao P., Ai L., Ni L., Lv X.*. Fabrication of zein nanoparticles with natural polyanion gum arabic for improving the hepatoprotective efficacy of ganoderic acids in mice with excessive alcohol intake. Int. J. Biol. Macromol., 2022. (Under review).

    30. Cao Y.#, Lin Y., Guo W., Lv X.*, Rao P., Ai L., Ni L.*. Evaluation of the hepatoprotective effects of ganoderic acids-loaded chitosan/zein nanoparticles in mice with excessive alcohol intake. Food & Function, 2022. (In preparation).

    31. Lin Y.#, Cao Y., Guo W., Han J., Chen G., Lv X.*, Rao P., Ni L.*. The beneficial effects of selenylated polysaccharides from Auricularia auricula on liver metabolism function and intestinal microbiota in mice with excessive alcohol intake. Int. J. Biol. Macromol., 2022. (In preparation).

    32. Lin Y.#, Cao Y.#, Guo W.#, Wu Q., Li J., Lv X.*, Rao P., Ni L.*. The ameliorative effects and mechanisms of selenium-enriched yeast on liver metabolism function and intestinal microbiota in mice with excessive alcohol intake. Food Res. Int., 2022. (In preparation).

    33. Guo W.#, Chen M.#, Pan W., Zhang Q., Xu J., Lin Y., Li L., Liu B., Bai W., Zhang Y., Ni L., Rao P., Lv X.*. Hypoglycemic and hypolipidemic mechanism of organic chromium derived from the chelation of Grifola frondosa polysaccharide-chromium (III) and its modulation of intestinal microflora in high fat-diet and STZ-induced diabetic mice. Int. J. Biol. Macromol., 2020, 145: 12081218.

    34. Guo W.#, Deng J.#, Pan Y., Xu J., Hong J., Shi F., Liu G., Qian M., Bai W., Zhang W., Liu B., Zhang Y., Luo P., Ni L., Rao P., Lv X.*. Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides and their relationships with the modulation of intestinal microflora in diabetic mice induced by high-fat diet and streptozotocin. Int. J. Biol. Macromol., 2020, 153: 1231-1240.

    35. Hong J.#, Wu L.#, Lu J., Zhou W., Cao Y., Lv W., Liu B.*, Rao P., Ni L., Lv X.*. Comparative transcriptomic analysis reveals the regulatory effects of inorganic nitrogen on the biosynthesis of Monascus pigments and citrinin. RSC Advances, 2020, 10: 52685282.

    36. Chen M.#, Guo W.#, Li Q., Xu J., Cao Y., Liu B., Yu X.*, Rao P., Ni L., Lv X.*. The protective mechanism of Lactobacillus plantarum FZU3013 against non-alcoholic fatty liver associated with hyperlipidemia in mice fed a high-fat diet. Food & Function, 2020, 11(4): 33163331.

    37. Zhang Q.#, Fan X.#, Guo W., Cao Y., Lin Y., Cheng W., Chen L.*, Rao P., Ni L., Lv X.*. The protective mechanisms of macroalgae Laminaria japonica consumption against lipid metabolism disorders in high-fat diet-induced hyperlipidemic rats. Food & Function, 2020, 11(4): 32563270.

    38. Zhang Q.#, Fan X.#, Ye R., Hu Y., Zheng T., Shi R., Cheng W., Lv X.*, Chen L.*, Liang P.*. The Effect of Simvastatin on Gut Microbiota and Lipid Metabolism in Hyperlipidemic Rats Induced by a High-Fat Diet. Front. Pharmacol., 2020, 11: 522. doi: 10.3389/fphar.2020.00522.

    39. Tong A., Hu R., Wu L., Lv X., Li X., Zhao L.*, Liu B.*. Ganoderma polysaccharide and chitosan synergistically ameliorate lipid metabolic disorders and modulate gut microbiota composition in high fat diet-fed golden hamsters. J. Food Biochem., 2020, 44 (1), e13109.

    40. Huang Z.#, Deng J.#, Li Q., Cao Y., Lin Y., Bai W., Liu B., Ni L., Rao P., Lv X.*. Protective Mechanism of Common Buckwheat (Fagopyrum esculentum Moench.) against Nonalcoholic Fatty Liver Disease Associated with Dyslipidemia in Mice Fed a High-Fat and High-Cholesterol Diet. J. Agric. Food Chem., 2020, 68: 6530–6543.

    41. Guo W.#, Guo J.#, Liu B., Lu J., Chen M,, Liu B., Bai W., Rao P., Ni L., Lv X.*. Ganoderic acid A from Ganoderma lucidum ameliorates lipid metabolism and alters gut microbiota composition in hyperlipidemic mice fed a high-fat diet. Food & Function, 2020,11: 68186833. [封面文章]

    42. Huang Z., Chen M., Guo W., Li T., Liu B.*, Bai W., Ai L., Rao P., Ni L., Lv X.*. Monascus purpureus-fermented common buckwheat protects against dyslipidemia and non-alcoholic fatty liver disease through the regulation of liver metabolome and intestinal microbiome. Food Res. Int., 2020, 136: 109511. DOI: 10.1016/j.foodres.2020.109511.

    43. Deng J.#, Guo W.#, Guo J.#, Li Y, Zhou W., Lv W., Li L., Liu B., Xia G.*, Bai W., Rao P., Ni L., Lv X.*. Regulatory effects of a Grifola frondosa extract rich in pseudobaptigenin and cyanidin-3-O-xylosylrutinoside on glycolipid metabolism and the intestinal flora in high-fat diet-fed rats. J. Func. Foods, 2020. DOI: 10.1016/j.jff.2020.104230.

    44. Zhang J., Zhang C., Wu W., Lv X., et al. Correlation of the bacterial communities with umami components, and chemical characteristics in Zhejiang xuecai and fermented brine. Food Res. Int., 2020, 140(3): 109986.

    45. Hong J., Chen M., Zhou W., Guo W., Li L., Huang Z., Liu B.*, Bai W., Ni L., Rao P., Lü X.*. Effects of Lactic Acid Bacteria on the Growth of Yeast and the Formation of Flavor Compounds in the Fermentation of Hongqu Glutinous Rice Wine. Journal of Chinese Institute of Food Science and Technology, 2020, 20(1): 91100.

    46. Deng J., Guo W., Zhou W., Hong J., Li L., Liu H., Liu B., Chen S., Ni L., Rao P., Lü X.*. Comparison of Enzymes Production of Different Types of Filamentous Fungi and Studies on the Fermentation Characteristics of Mixed Cultures Based on Glutinous Rice. Journal of Chinese Institute of Food Science and Technology, 2020, 20(1): 101108.

    47. Zhou W., Hong J., Li L., Li Y., Huang Z., Guo W., Ni L., Rao P., Liu B.*, Lü X.*. Screening of Components for Improving Lipid Metabolism in Grifola frondosa and Optimization of Its Extraction Technology. Journal of Chinese Institute of Food Science and Technology, 2020, 20(2): 145153.

    48. Li L., Guo W., Zhou W., Lin Y., Hong J., Liu H., Liu B.*, Ni L. Rao P., Lü X.*. The Effects of Hongqu and Baiqu on the Formation of Aroma Components in Hongqu Rice Wine. Journal of Chinese Institute of Food Science and Technology, 2020, 20(2): 205211.

    49. Lv X.*, Guo W., Li L., Yu X., Liu B.*. Polysaccharide peptides from Ganoderma lucidum ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet-fed rats. J. Func. Foods, 2019, 57: 48–58.

    50. Li L., Guo W., Zhang W., Xu J., Qian M., Bai W., Zhang Y., Rao P., Ni L., Lv X.*. Grifola frondosa polysaccharides ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet fed rats. Food & Function, 2019, 10, 2560–2572.

    51. Huang Z., Guo W., Zhou W., Li L., Xu J., Hong J., Liu H., Zeng F., Bai W., Liu B.*, Ni L., Rao P., Lv X.*. Microbial communities and volatile metabolites in different traditional fermentation starters used for Hong Qu glutinous rice wine. Food Res. Int., 2019, 121: 593–603.

    52. Guo W., Shi F., Li L., Xu J., Chen M., Wu L., Hong J., Qian M., Bai W., Liu B., Zhang Y., Ni L., Rao P., Lv X.*. Preparation of a novel Grifola frondosa polysaccharide-chromium (III) complex and its hypoglycemic and hypolipidemic activities in high fat diet and streptozotocin-induced diabetic mice. Int. J. Biol. Macromol., 2019, 131: 81–88.

    54. Zhou W., Guo R., Guo W., Hong J., Li L., Ni L., Sun J.*, Liu B., Rao P., Lv X.*. Monascus yellow, red and orange pigments from red yeast rice ameliorate lipid metabolic disorders and gut microbiota dysbiosis in Wistar rats fed on a high-fat diet. Food & Function, 2019, 10: 1073–1084.

    55. Jiang Y.#, Lv X.#, Zhang C., Zheng Y., Zheng B., Duan X., Tian Y.*. Microbial dynamics and flavor formation during the traditional brewing of Monascus vinegar. Food Res. Int., 2019, 125, 108531. (#co-first author)

    56. Li L., Xu J., Cao Y., Lin Y., Liu J., Guo W., Bai W., Zhang Y., Ni L., Liu B., Rao P., Lv X.*. Preparation of a novel Ganoderma lucidum polysaccharide-chromium (III) complex and its hypoglycemic and hypolipidemic activities in high-fat and high-fructose diet-induced pre-diabetic mice. Int. J. Biol. Macromol., 2019, 140: 782–793.

    57. Chen H., Zeng F., Li S., Liu Y., Gong S., Lv X., Zhang J., Liu B.*. Spirulina active substance mediated gut microbes improve lipid metabolism in high-fat diet fed rats. J. Func. Foods, 2019, 59: 215222.

    58. Pan Y., Wan X.,Zeng F., Zhong R., Guo W., Lv X., Zhao C., Liu B.*. Regulatory effect of Grifola frondosa extract rich in polysaccharides and organic acids on glycolipid metabolism and gut microbiota in rats. Int. J. Biol. Macromol., 2019. doi: 10.1016/j.ijbiomac.2019.11.067.

    59. Lv X., Jiang Y., Hu R., Guo W., Zhou W., Li Y., Rao P., Chen J.*, Ni L.*. Studies on the characteristics of volatile flavor components in traditional fermentation starters for Hong Qu glutinous rice wine brewing. Journal of Chinese Institute of Food Science and Technology, 2019, 19(5): 222233.

    60. Zhou W., Huang Z., Hong J., Li L., Guo W., Jiang Y., Liu B., Ni L., Rao P., Chen J.*, Lv X.*. The double direction regulatory mechanism of ammonium chloride on pigments and citrinin of Monascus purpureus in solid-state fermentation. Journal of Chinese Institute of Food Science and Technology, 2019, 19(6): 8189.

    61. Li L., Lv Y., Guo W., Pan Y., Hong J., Zhao L., Ni Li, Rao P., Li Q., Lv X.*. Analysis of microbial flora and volatile flavor components in traditional fermentation starters for Hongqu glutinous rice wine. Food Science, 2019, 40(2): 7984.

    62. Hong J., Li Q., Pan Y., Guo W., Huang Z., Zhao L., Qian M., Bai W., Ni L., Rao P., Liu B., Lv X.*. Changes in volatile metabolites and microbial community dynamics during the traditional brewing of Hongqu glutinous rice wine. Food Science, 2019, 40(12): 137144.

    63. Guo W., Pan Y., Li L., Li T., Liu B.*, Lv X.*. Ethanol extract of Ganoderma lucidum ameliorates lipid metabolic disorders and modulates gut microbiota composition in high-fat diet fed rats. Food & Function, 2018, 9: 34193431.

    64. Hu R., Guo W., Huang Z., Li L., Liu B.*, Lv X.*. Extracts of Ganoderma lucidum improve lipid metabolism and modulate gut microbiota in high-fat diet fed rats. J. Func. Foods, 2018, 46: 403412.

    65. Huang Z., Hong J., Guo W., Pan Y., Li L., Zhao L.*, Liu B., Chen S., Bai W., Rao P., Ni L., Lv X.*. Exploring core functional microbiota responsible for the production of volatile flavour during the traditional brewing of Wuyi Hong Qu glutinous rice wine. Food Microbiol., 2018, 76: 487–496.

    66. Zhao C , Yang C , Chen M , Lv X., Liu B. , & Yi, L.. Regulatory Efficacy of Brown Seaweed Lessonia nigrescens Extract on the Gene Expression Profile and Intestinal Microflora in Type 2 Diabetic Mice. Molecular Nutrition & Food Research, 2017:1700730.

    67. Huang Z., Zhou W., Yang X., Tong A., Hong J., Guo W., Li T., Jia R., Pan Y., Lin J., Lv X.*, Liu B.*. The regulation mechanisms of soluble starch and glycerol for production of azaphilone pigments in Monascus purpureus FAFU618 as revealed by comparative proteomic and transcriptional analyses. Food Res. Int., 2018, 106: 626–635.

    68. Chen Y., Liu Y., Sarker M M R., Yan X., Yang C., Zhao L., Lv X.*, Liu B., Zhao C.*. Structural characterization and antidiabetic potential of a novel heteropolysaccharide from Grifola frondosa via IRS1/PI3K-JNK signaling pathways. CARBOHYD. POLYM., 2018, 198: 452–461.

    69. 呂旭聰, 劉志彬, 張雯, 唐薇, 陳芳, 張雅妮, 饒平凡, 倪莉*. 紅曲黃酒傳統釀造過程中優勢細菌活菌檢測方法的構建及應用. 中國食品學報, 2018, 18(07)210–219.

    70. 呂旭聰, 劉志彬, 張雯, 陳芳, 黃若蘭, 翁星, 饒平凡, 倪莉*.  紅曲黃酒傳統釀造體系中真菌菌群多樣性分析方法的構建及其應用. 中國食品學報, 2018, 18(08)214–223.

    利:

    至今已申請國家發明專利18項(授權9項),其中,第一發明人專利9項(授權2項)。

    (1)一種高純度灰樹花多酚組分的制備方法,授權編號ZL201610082919.9(第一發明人,已轉化)

    (2)一種固態發酵制備高色價紅曲產品的方法,授權編號ZL201510142975.2(第一發明人)

    (3)一種具有抗氧化活性的灰樹花蛋白酶解物的制備方法,授權編號ZL201510192089.0(第二發明人,已轉化)

    (4)一種能源草和禽畜糞便的資源化利用方法,授權編號ZL201510065687.1(第四發明人,已轉化)

    (5)一種確定多年生沼氣專用能源植物最佳采收期的方法,授權編號ZL201510062069.1(第四發明人)

    (6)一種能源草液固聯合沼氣發酵系統,授權編號ZL201510093785.6 (第五發明人)

    (7)一種能源草的綜合利用方法,授權編號ZL201510062564.2(第五發明人,已轉化)

    (8)一種滸苔的綜合利用方法,授權編號ZL201510065595.3(第五發明人,已轉化)

    (9)一種利用能源草和大型海藻共同發酵制備生物燃氣的方法,授權編號ZL201410041569.2(第六發明人)

    獲獎及其他

    1. 福建省科學技術進步獎二等獎(2017年,排名第五)

    2. 福建省自然科學杰出青年基金獲得者(2019年)

    3. 中國食品科學技術學會科學技術進步獎二等獎(2016年,排名第五)

    4. 福建省自然科學學術論文一等獎(2014年,排名第一)、二等獎(2016年,排名第一)

    5. 中國博士后科學基金一等資助<食品科學與工程,2015年>

    6. 中國博士后科學基金特別資助<食品科學與工程,2016年>

    7. 國際食品微生物標準委員會-中國食品安全2012年國際研討會優秀論文獎

    8. <International Journal of Food Microbiology> 國際SCI期刊“杰出審稿”專家

    9. <Food & Function> 國際SCI期刊“杰出審稿”專家

    10. <International Journal of Biological Macromolecules>國際SCI期刊“杰出審稿”專家

    課題組學習生活、辦公及科研環境

    本課題組隸屬于福州大學食品科技研究所(福大旗山校區科技園)、福州大學食品營養與健康研究中心(福大晉江校區),位于福州大學國家大學科技園,是福建省食品科學技術學會掛靠單位,同時還是福建省食品生物技術創新工程技術研究中心。目前課題組配備有研究生休息室、食品工藝室、食品生化實驗室、超凈工作室、微生物發酵間、分子生物學實驗室、清潔級動物房、無菌細胞實驗室、色譜分析儀器室等,研究生辦公及科研實驗條件非常優越。



    人体色图