教育工作經歷：

2015.08 至今 福州大學生物科學與工程學院 講師/副教授

2012.07 - 2015.07 中科院蘇州納米所 助理研究員

2009.09 - 2012.06 北京大學，前沿交叉學科研究院 博士

2006.09 - 2009.06 北京大學，工學院，生物醫學工程系 碩博連讀

2002.09 - 2006.06 北京大學，化學與分子工程學院 學士

教學簡介：

研究生課程：現代儀器分析，生物材料工程

本科課程：組織工程學，生物醫用材料

科研簡介：

聚焦于可與生命體協同作用的功能性高分子應用研究，及其在生物分析與治療等領域的拓展與應用。主要研究方向：蛋白質與功能高分子偶聯技術；細菌負載醫用材料；細菌耐藥性快篩材料與生物芯片等。歡迎感興趣的同仁合作，歡迎有想法的同學加入。

社會兼職：

Frontiers in Chemistry - Review Editor. Cell Reports Physical Science, Biomacromolecules, Analyst, Sci. Rep. 等學術期刊審稿人。

科研項目：

國家自然科學基金青年基金項目，21504105

國家自然科學基金應急管理項目，21444007

福建省自然科學基金項目，2024J01269

福建省自然科學基金項目，2020J05109

江蘇省基礎研究計劃項目，BK20130345

代表性論文：（*為通訊作者）

1. Yuanzi Wu, Kaiqiang Zhou, Wenhui Li, Min Huan, Zhichao Yu, Fen Yan, Huixiao Hong, Dianping Tang*, Yansong Guo*, Zuquan Weng*. Microbe-imprinted polymers for rapid drug-resistant bacteria recognition Chem. Eng. J. 2025. 512, 162543. 10.1016/j.cej.2025.162543

2. Yuanzi Wu*, Yanwei Lyu, Ling Li, Kaiqiang Zhou, Jingwen Cai, Xuwei Wang, Huiru Wang, Fen Yan, & Zuquan Weng*. Unimolecular Cascaded Multienzyme Conjugates Modulate the Microenvironment of Diabetic Wound to Promote Healing. Biomacromolecules 2024, 25, 43-54. 10.1021/acs.biomac.3c00698

3. Huiru Wang^?, Shanyun Ma^?, Muyan Diao, Li Wenhui, Min Huan, Xiaofang Sun and Yuanzi Wu*. Engineering Thermoresponsive Enzyme–Polymer Conjugates via Glycan-Selective In Situ Polymerization for Recyclable Homogeneous Biocatalysis. Biomacromolecules 2024.25. 7951-7957. 10.1021/acs.biomac.4c01220

4. Jingjing Shu^?; Wenli Xiong^?; Ran Zhang; Shanyun Ma; Kaiqiang Zhou; Xuwei Wang; Fen Yan; Da Huang; Jianhua Li; Yuanzi Wu*, Jian'an He*. Glycan-selective in-situ growth of thermoresponsive polymers for thermoprecipitation and enrichment of N-glycoprotein/glycopeptides. Talanta 2023, 253, 123956. 10.1016/j.talanta.2022.123956

5. Xueran Bi^?; Wenli Xiong^?; Jian’an He; Shanyun Ma; Jiangsheng Zhang; Yuan Fang & Yuanzi Wu*. Site-Selective and Biocompatible Growth of Polymers from Glycan Moieties of Glycoproteins and Living Cells. Biomacromolecules 2021, 22, 4237-4243. 10.1021/acs.biomac.1c007

6. Yanqiu Chen^?; Mei Wan^?; Yi Zhong; Tingfang Gao; Yuehan Zhang; Fen Yan; Da Huang; Yuanzi Wu* & Zuquan Weng*. Partially Hydrolyzed Guar Gum Modulates Gut Microbiota, Regulates the Levels of Neurotransmitters, and Prevents CUMS-Induced Depressive-Like Behavior in Mice. Mol. Nutr. Food Res. 2021, 2100146. 10.1002/mnfr.202100146

7. T. F. Gao; Y. H. Shi; Y. Xue; F. Yan; D. Huang; Y. Z. Wu* & Z. Q. Weng*. Polyphenol extract from superheated steam processed tea waste attenuates the oxidative damage in vivo and in vitro. J. Food Biochem., 2020, 44, e13096.

8. Y. Z. Wu*; S. G. Wu^?; S. Y. Ma^?; F. Yan & Z. Q. Weng*. Cytocompatible Modification of Thermoresponsive Polymers on Living Cells for Membrane Proteomic Isolation and Analysis. Anal. Chem., 2019, 91, 3187-3194.

9. Y. Z. Wu*; Z. Cai; S. G. Wu; W. L. Xiong & S. Y. Ma. Protein purification by chemo-selective precipitation using thermoresponsive polymers. Biopolymers, 2018, 109, e23222.

10. Y. Z. Wu*; C. Yan; J. A. He*; W. L. Xiong; S. G. Wu; S. T. Liu & Z. Cai. Reversible mannosylation as a covalent binding adjuvant enhances immune responses for porcine circovirus type 2 vaccine. ACS OMEGA, 2018, 3, 17341-17347.

11. Y. Z. Wu; Y. Jiang; X. S. Zheng; S. S. Jia; Z. Zhu; B. Ren* & H. W. Ma*. Facile fabrication of micro?uidic surface-enhanced Raman scattering devices via lift-up lithography. R. Soc. Open Sci., 2018, 5, 172034.

12. Y. Z. Wu; Y. Y. Huang & H. W. Ma*. J. Am. Chem. Soc., 2007, 129, 7226-7227.

13. Y. Z. Wu; S. R. Coyer; H. W. Ma & A. J. García*. Acta Biomater., 2010, 6, 2898-2902.

授權發明專利：

一種對細胞進行高分子功能化修飾的方法 ZL 2021 1 0828968.3

一種無泄漏封包酵母水凝膠及其制備方法 ZL 2022 1 0103555.3

獲獎情況:

2012年，北京市優秀畢業生

2012年，北京大學優秀畢業生