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  • 生物科學與工程學院

    College of Biological Science and Engineering

    王國增

    發布日期:2019-12-08 發布者:生工學院

     

    姓名:王國增

    性別:男

    職稱:副研究員

    學歷:博士

    電話:

    電子郵件:wanggz@fzu.edu.cn

    研究方向:1.極端酶功能及應用;2.合成生物學;3.酶工程

    教育工作經歷:

    2002-2006:東北農業大學,學士

    2006-2011:中國農業科學院研究生院,博士

    2011-2013:中國農業科學院生物技術研究所,助理研究員

    2017-2018:德國漢堡大學,訪問學者

    2013-今:福州大學生物科學與工程學院,副研究員

    教學簡介:

    本科生課程:蛋白質與酶工程,基因工程

    研究生課程:現代微生物生物技術,應用蛋白質化學

    科研簡介:

    在極端環境微生物酶發掘、酶的結構功能、合成生物學等領域進行了深入研究。主持國家自然基金青年基金項目1項,福建省高校杰出青年人才項目1項,福建省自然科學基金項目、校人才基金和校科技發展基金等共4項,作為課題骨干參加國家863項目1項。在Bioresource TechnologyScientific ReportsPLoS ONEApplied   Microbiology and BiotechnologyBiochemical   and Biophysical Research Communications等刊物上發表SCI論文25篇,其中以第一作者或通訊作者發表17篇。申請發明專利6, 其中獲得授權4項。

    社會兼職:

    福建省微生物學會理事

    科研項目:

    1. 福建省自然科學基金,2019J01237,瘤胃微生物木聚糖酶基因在食物消化周期中的表達規律及功能特性研究,2019.06-2022.05,主持。

    2. 福建省高校杰出青年科研人才計劃,SW2015-01,宏基因組技術發掘和利用鹽堿湖中極端微生物堿性酶基因資源,2015.07-2017.12,主持。

    3. 福建省自然科學基金,2015J05066,大布蘇鹽堿湖底泥微生物宏基因組中新木聚糖酶基因克隆表達及其特性研究,2015.04-2018.03,主持。

    4. 國家自然科學基金青年基金項目,31301406,山羊瘤胃微生物宏基因組來源的低溫木聚糖酶XynGR40冷適應機制的研究,2014.01-2016.12,主持。

    5、校人才基金,XRC-1326,鹽堿湖微生物木聚糖酶基因多樣性及新基因克隆和酶特性研究,2013.06-2015.08,主持。

    6、校科技發展基金,2013-XY-16,北極海洋底泥微生物新木聚糖酶基因克隆及酶學特性研究, 校科技發展基金, 2013.07-2015.12,主持

    7、國家高技術研究發展計劃,2012AA022105,基因組多位點快速進化與改良,2012.12-2015.12,參與。

    專利

    (1)一種堿性耐鹽普魯蘭酶PulA及其基因和應用,2017, 專利號: ZL201710584710.7

    (2)一種木聚糖酶XynMF10及其基因和應用,2017, 專利號: ZL 201710584732.3

    (3) 一種耐鹽耐有機溶劑的低溫堿性酯酶EstSL3及其基因和應用,2015, 專利號:ZL201510668911.6

    (4) 一種低溫木聚糖酶XYNGR40及其基因和應用,2010,專利號:ZL201010238563.6

    (5) 一種高溫堿性耐鹽木聚糖酶XynSL4及其基因和應用,2014, 申請號:   CN201410629920.X

    (6)一種極端嗜鹽、耐表面活性劑的非鈣離子依賴型α-淀粉酶及其基因和應用,2019, 申請號: CN109628429A

    以第一作者或通訊作者發表的論文:(*為通訊作者)

    [1] Ren Y, Luo H, Huang H, Hakulinen N, Wang Y,   Wang Y, Su X, Bai Y, Zhang J, Yao B, Wang G*, Tu T*, Improving the   catalytic performance of Proteinase K from Parengyodontium album for   use in feather degradation, International Journal of Biological   Macromolecules 154 (2020) 1586-1595

    [2] Xiao Q, Han J,   Jiang C, Luo M, Zhang Q, He Z, Hu J*, Wang G*, Novel Fusion Protein   Consisting of Metallothionein, Cellulose Binding Module, and Superfolder GFP   for Lead Removal from the Water Decoction of Traditional Chinese Medicine.   ACS Omega, 5 (2020) 2893-2898

    [3] G. Wang*, Y.   Ren, T.B. Ng, W.R. Streit, X. Ye, High-throughput amplicon sequencing   demonstrates extensive diversity of xylanase genes in the sediment of soda   lake Dabusu, Biotechnology Letters 41(3) (2019) 409-418

    [4] G.   Wang*, M. Luo, J. Lin, Y. Lin, R. Yan, W.R. Streit, X. Ye A new extremely   halophilic, calcium-independent and surfactant- resistant alpha-amylase from Alkalibacterium sp. SL3, Journal of   Microbiology and Biotechnology 29 (2019) 765-775.

    [5] J. Wu, R. C. Qiu, Y. Ren, Yan, X. Ye, G. Wang*, Novel salt-tolerant   xylanase from a mangrove-isolated fungus Phoma   sp. mf13 and its application in Chinese steamed bread, ACS Omega 3 (2018)   3708-3716.

    [6] G.   Wang, J. Wu, R. Yan, J. Lin*, X. Ye*, A Novel Multi-domain High   Molecular, Salt-Stable Alkaline Xylanase from Alkalibacterium sp. SL3, Frontiers in Microbiology 7 (2017) 2120.

    [7] G.   Wang, J. Wu, J. Lin, X. Ye*, B. Yao*, The disruption of two salt bridges   of the cold-active xylanase XynGR40 results in an increase in activity, but a   decrease in thermostability, Biochemical and Biophysical Research Communications   481(1-2) (2016) 139-145.

    [8] G.   Wang, Q. Wang, X. Lin, T.B. Ng, R. Yan, J. Lin*, X. Ye*, A novel   cold-adapted and highly salt-tolerant esterase from Alkalibacterium sp. SL3 from the sediment of a soda lake,   Scientific Reports 6 (2016) 19494.

    [9] X. Huang, J. Lin, X. Ye, G. Wang*, Molecular characterization of a thermophilic and salt-   and alkaline-tolerant xylanase from Planococcus   sp. sl4, a strain isolated from the sediment of a soda lake, Journal of Microbiology   and Biotechnology 25(5) (2015) 662-671.

    [10] G.   Wang, X. Huang, T.B. Ng, J. Lin*, X.Y. Ye*, High phylogenetic diversity   of glycosyl hydrolase family 10 and 11 xylanases in the sediment of Lake   Dabusu in China, PloS One 9(11) (2014) e112798.

    [11] G.   Wang, K. Meng, H. Luo, Y. Wang, H. Huang, P. Shi, P. Yang, Z. Zhang*, B.   Yao*, Phylogenetic diversity and environment-specific distributions of   glycosyl hydrolase family 10 xylanases in geographically distant soils, PloS One   7(8) (2012) e43480.

    [12] Y. Li#, G. Wang#, J. Tian, H. Liu, H. Yang, Y. Yi, J. Wang, X.   Shi, F. Jiang, B. Yao*, Z. Zhang*, Transcriptome analysis of the silkworm   (Bombyx mori) by high-throughput RNA sequencing, PloS One 7(8) (2012) e43713.

    [13] G.   Wang, K. Meng, H. Luo, Y. Wang, H. Huang, P. Shi, X. Pan, P. Yang, B.   Yao*, Molecular cloning and characterization of a novel SGNH arylesterase   from the goat rumen contents, Applied Microbiology and Biotechnology 91(6)   (2011) 1561-1570.

    [14] G.   Wang, H. Luo, Y. Wang, H. Huang, P. Shi, P. Yang, K. Meng, Y. Bai, B.   Yao*, A novel cold-active xylanase gene from the environmental DNA of goat   rumen contents direct cloning, expression and enzyme characterization,   Bioresource Technology 102(3) (2011) 3330-3336.

    [15] G.   Wang, H. Luo, K. Meng, Y. Wang, H. Huang, P. Shi, X. Pan, P. Yang, Q.   Diao, H. Zhang, B. Yao*, High genetic diversity and different distributions   of glycosyl hydrolase family 10 and 11 xylanases in the goat rumen, PloS One   6(2) (2011) e16731.

    [16] G.   Wang, Y. Wang, P. Yang, H. Luo, H. Huang, P. Shi, K. Meng, B. Yao*,   Molecular detection and diversity of xylanase genes in alpine tundra soil,   Applied Microbiology and Biotechnology 87(4) (2010) 1383-1393.

    [17] H. Huang#, G. Wang#, Y. Zhao, P. Shi, H. Luo, B. Yao*, Direct and   efficient cloning of full-length genes from environmental DNA by RT-qPCR and   modified TAIL-PCR, Applied Microbiology and Biotechnology 87(3) (2010) 1141-1149.

    獲獎情況

    中國農業科學院優秀博士論文(2012

    福建省高校杰出青年人才(2015

    指導研究生獲得福建省優秀碩士論文(2017

     

    人体色图